Holy Cross Hospital is a Catholic hospital located at 2701 West 68th Street, across from Marquette Park in Chicago's West Lawn neighborhood on the city's southwest side. The hospital was founded by the Sisters of Saint Casimir, who's motherhouse is nearby. Founded in 1927, Holy Cross Hospital is a not-for-profit neighborhood health system located in 3 locations throughout Chicago's southwest neighborhoods and suburbs. It serves public safety and help when needed, receiving the highest number of ambulance runs per year of any other hospital in the state of Illinois.
In March 2009, Holy Cross completed an expansion of the Emergency Department, with the addition of 14 monitored patient rooms.
In December 2010, Chicago Cardinal Francis Eugene George, OMI, announced that Holy Cross Hospital would become a for-profit Catholic hospital, a seemingly counter-intuitive move, and be acquired by Vanguard Health Systems of Nashville, Tennessee. It would still be considered Catholic because the Sisters would still have some reserved powers and the hospital would have to comply with the Ethical and Religious Directives for Catholic Health Care Systems, and because the Archbishop and the Holy See had both approved the unique transaction, given that no suitable Catholic or non-Catholic not-for-profit partner could be found.
However, in August 2011 the transaction was cancelled, with both parties citing downshifts in the economy, as well as changes in Medicare and Medicaid, as the major factors of dissolving the partnership.